The eyelids protect the eye physically, by blinking, which protects the ocular surface from noxious insult and facilitates tear spreading via secretion of lipids from the meibomian glands. Involutional or iatrogenic eyelid changes can influence eyelid function, potentially leading to dry eye. This results in tear hyper-evaporation that drives hyperosmolarity, accompanied by symptoms of irritation and variable vision as well as inflammation and epiphora.
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