The World Council of Optometry (WCO) and Alcon have engaged international dry eye specialists, Professors James Wolffsohn (Aston University, UK), Jennifer Craig (Auckland University, New Zealand) and Lyndon Jones (Waterloo University, Canada) to develop education tools for eyecare practitioners acro
Ocular graft-versus-host disease (oGvHD) manifests in 60-80% of patients undergoing allogeneic haematopoietic stem cell transplantation, due to donor T cells incorrectly identifying recipient tissue as foreign, leading to an immunological attack by the donor cells1.
The Save Sight Dry Eye Registry (SSDR) is the first multinational, web-based interdisciplinary registry able to collect high-quality outcome data from dry eye patients in clinical settings. With over 35 clinicians at 30 sites in Australia, New Zealand, Spain, Germany and the UK, the registry has gro
Activation and elevation of inflammatory mediators is associated with the pathogenesis and progression of dry eye disease (DED)¹. The quantification of inflammatory marker levels can provide insight into the disease progression and severity and may help guide individualised treatment. However, a var
The misconception that dry eye disease (DED) primarily affects the elderly presents a risk of overlooking issues in children. DED has been reported in paediatric populations with a prevalence of up to 33%1. As in adults, risk factors for paediatric DED include diabetes, Sjögren’s syndrome, blepharok
The prevalence and severity of dry eye disease (DED) is known to increase with age1. However, several recent studies have reported a high prevalence in younger populations. Increased digital screen use, particularly during the Covid-19 pandemic, has been associated with symptomatic DED in 70.8% of u
The common use of oral antibiotics in the management of meibomian gland dysfunction (MGD) is an extension of the traditional dermatological approach to rosacea treatment. In this context, historically, oral tetracyclines have been used for their anti-inflammatory properties (anti-matrix metalloprote
In Covid-affected 2021, three BOptom students joined the OSL team to explore the effects of an oral astaxanthin (AXT)-based supplement under the supervision of Professor Jennifer Craig, Dr Alex Muntz and myself. The team recruited 30 participants with mild-to-moderate dry eye disease (DED), who took
Ocular surface pain is a leading cause of eyecare visits and healthcare costs, having an observable negative impact on quality of life1. As a consequence of both ocular and systemic disorders, and driven by various mechanisms that are often difficult to fully elucidate, ocular surface pain is often
A Chinese study has revealed a significant correlation between dry eye disease (DED) and anxiety and depression, with researchers proposing sleep quality acts as a mediator between the conditions.
A sequence-randomised, double-masked, vehicle-controlled crossover clinical trial of Aldeyra’s 0.25% reproxalap ophthalmic solution have shown it was statistically superior to placebo for both primary endpoints of ocular redness in a dry eye chamber and Schirmer test after a single day of dosing.
An Austrian phase 2 study showed topical oestradiol reduced signs and symptoms of dry eye disease (DED) in postmenopausal women for at least three months.
