Researchers at Moorfields Eye Hospital said they identified markers from OCT retinal scans which identified Parkinson’s disease in patients, on average, seven years before they were diagnosed.
The team, led by Dr Siegfried Wagner and Professor Pearse Keane of Moorfields and UCL Institute of Ophthalmology, found Parkinson’s patients had differences in thickness in their retina’s inner nuclear layer (INL) and ganglion cell-inner plexiform layer (GCIPL). Using artificial intelligence (AI), images from INSIGHT, the world's largest database of retinal images and associated clinical data, were screened for these differences. The team then validated their model using data from the UK Biobank.
