Scientists at Zhongshan University in Guangzhou have developed a smart contact lens that can detect changes in intraocular pressure (IOP) and administer glaucoma medication on demand.
Tiny sensors on the wireless, double-layer contact lens (CL) measure IOP changes and a hydrogel layer stores and delivers glaucoma medication to the cornea using a weak electrical current. When IOP reaches a certain threshold, the sensors are squeezed together, creating an electrical signal that triggers delivery of an anti-glaucoma medicine.
Testing the device on rabbits, investigators found the smart CL lowered IOP by about one-third within 30 minutes and helped maintain those levels for a longer when compared to delivery of the same drug via eye drop. While it is still unknown how well the device will work in humans, researchers said the minimally invasive and battery-free device has the potential for large-scale production as its manufacturing process is compatible with the commercial production of printed circuit boards.
The research was published by Nature Communications.
For more, see www.eyeonoptics.co.nz/articles/archive/drug-eluting-cl-shows-promise-for-glaucoma
