Herpes zoster (shingles) represents reactivation of latent herpes zoster virus in individuals with previous chickenpox infection. It occurs in one in three individuals over their lifetime, with significant sequelae, including recurrent episodes and post-herpetic neuralgia, which is pain that persists after the rash heals and is associated with depression. Herpes zoster also carries an increased risk of stroke and myocardial infarction1.
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