Ocular manifestations in Down Syndrome

Down Syndrome (DS), trisomy of chromosome 21, is one of the most common genetic causes of intellectual disability. It affects 50-80 newborns annually in New Zealand, with advanced maternal age being the primary risk factor. This article encompasses the ophthalmic impairment and clinical considerations for individuals with DS, however, other co-morbidities include hearing impairment, cardiac and respiratory anomalies.